During this period, research converged on inflammation as the central mechanism driving both acute lung injury and subsequent remodeling. Dominant patterns included endotoxin-triggered inflammation, cytokine-mediated fibrogenesis, and early recognition of airway remodeling as a determinant of chronic dysfunction. Methodological advances integrated in vivo and in vitro models with histopathology and functional assessment to unify inflammatory lung diseases under a remodeling paradigm.